purpose: to evaluate the vascular occlusion in coats’ disease   methods: in this non-comparative case series, 13 consecutive patients with coats’ disease from january 2011 to september 2011 were included. the hypercoagulability states were evaluated in these patients.   results: the mean age of the patients in this series was 15.4 years. all but one patient had high anti-cytomegalovirus antibod...

BACKGROUND Coats' disease is an uncommon form of retinal telangiectasis, and the identification of novel proteins that contribute to the development of Coats' disease is useful for improving treatment efficacy. Proteomic techniques have been used to study many eye diseases; however, few studies have used proteomics to study the development of Coats' disease. METHODS Isobaric tagging for relat...

Coats' disease is an idiopathic ophthalmic condition caused by a defect in the development of retinal vasculature, characterized by retinal telangiectasis, haemorrhages, intraretinal and subretinal exudation. There are two pathological processes, which are evident in Coats' disease. The first consists of a breakdown of the bloodretinal barrier at the endothelial level, which causes plasma leaka...

cur within a subretinal mass in Coats disease. To our knowledge, this is the first report of intraretinal calcification in Coats disease. Intraretinal calcification classically occurs in retinoblastoma; however, it may also be detected in retinocytoma, tuberous sclerosis, and epiretinal membranes. This case reinforces the importance of a complete ophthalmic history, examination, and ancillary t...

PURPOSE We report the detection of peripheral retinal vascular abnormalities in the fellow eye with normal fundus in children with unilateral Coats' disease. METHODS The clinical records of patients diagnosed with Coats' disease were retrospectively reviewed. We recorded the subjects' characteristics and obtained fundus photography and fluorescein angiography (FA) images. The main outcome mea...

We report a case of Coats disease in a 9-year-old boy who had a profound visual deficit and increasing pain in his right eye. Funduscopic examination revealed a complex, exudative retinal detachment with a subretinal mass and peripheral retinal telangiectasis. B-scan ultrasonography revealed a heterogeneously echogenic subretinal mass with several highly reflective foci consistent with calcific...

Coats' disease is characterized by abnormal retinal vascular development (so-called 'retinal telangiectasis') which results in massive intraretinal and subretinal lipid accumulation (exudative retinal detachment). The classical form of Coats' disease is almost invariably isolated, unilateral and seen in males. A female with a unilateral variant of Coats' disease gave birth to a son affected by ...

PURPOSE The purpose of this study was to investigate the serum hypercoagulability state and common viral and protozoan infections in Coats' disease versus a normal control group. MATERIALS AND METHODS In this comparative case series, 22 consecutive patients with Coats' disease and 19 non-Coats' patients undergoing lensectomy for congenital, traumatic, or senile cataract between January 2011 a...